The AHCRN is composed of 8 clinical sites in the US, Canada, and Europe

AHCRN Sites 10.17

Primary Investigator: Thomas Zwimpfer, MD, PhD, FRCSC

Location: 2329 West Mall, Vancouver, BC, Canada V6T 1Z4

Primary Investigator: Mark Hamilton, MDCM, FRCSC, FAANS

Location: 1403 29 Street NW, Calgary, AB, Canada T2N 2T9

Principal Investigator: Michael Williams, MD, FAAN

Location: 1959 NE Pacific St, Seattle, WA 98195

Principal Investigators: Sean Nagel, MD and James Liao, MD, PhD

Location: 9500 Euclid Ave, Cleveland, OH 44195

Principal Investigators: Abhay Moghekar, MBBS and Mark Luciano, MD, PhD

Location: 1800 Orleans St, Baltimore, MD 21287

Principal Investigators: Jeffrey Wisoff, MD and James Golomb, MD

Location: 650 W 168th Street, New York, NY 10032

Principal Investigator: Guy McKhann II, MD

Location: 333 E 38th Street, New York, NY 10016

Principal Investigator: Richard Edwards, MD, FRCS

Location: Senate House, Tyndall Ave, Bristol B28 1TH, United Kingdom

The AHCRN is currently enrolling patients!

Registry Eligibility:

  • All Transitioning Hydrocephalus Patients
  • All Arrested Hydrocephalus Patients
  • New Acquired Hydrocephalus Patients
  • New Normal Pressure Hydrocephalus Patients


For Researchers

The goal of the AHCRN is to be an open network engaged in concurrent multi-center clinical trials. Currently, the AHCRN is composed of 5 clinical sites, a data coordinating center, a cerebrospinal fluid (CSF) biobank, and an image depository. At this early juncture, the ACHRN is closed to additional sites.

If you would like more information regarding the AHCRN please contact:


Mark Hamilton, MDCM, FRCSC
Department of Clinical Neurosciences
University of Calgary, Foothills Hospital
Calgary, Alberta, Canada

CSF Biobank

Mark Luciano, MD, PhD
AHCRN Principal Investigator
Johns Hopkins Medical Center
Baltimore, MD